Dissociation of Automatic and Strategic Lexical-Semantics: Functional Magnetic Resonance Imaging Evidence for Differing Roles of Multiple Frontotemporal Regions

• DOI: 10.1523/jneurosci.0808-06.2006
• Publication Date: 2006-06-14T17:44:53Z
• Authors: B. T. Gold; D. A. Balota; S. J. Jones; D. K. Powell; C. D. Smith; A. H. Andersen
• Keywords: Priming (agriculture)

Behavioral research has demonstrated three major components of the lexical-semantic processing system: automatic activation semantic representations, strategic retrieval and inhibition competitors. However, these component processes are inherently conflated in explicit decision tasks typically used functional magnetic resonance imaging (fMRI) research. Here, we combine logic behavioral priming studies neurophysiological phenomenon fMRI to dissociate neural bases across a series studies. A single lexical task was all studies, with stimulus onset asynchrony or linguistic relationship between prime target being manipulated. Study 1 left mid-fusiform gyrus (mid-FFG) five regions: middle temporal (MTG), bilateral anterior cingulate, inferior prefrontal cortex (aLIPC), posterior LIPC (pLIPC). These effects were explored more detail two subsequent 2 replicated effect mid-FFG that this region is preferential for domain. 3 dissociation regions contributing effect. Strategic facilitation observed aLIPC MTG, whereas pLIPC cingulate. provide reproducible evidence well established system.