Phase Advancement and Nucleus-Specific Timing of Thalamocortical Activity during Slow Cortical Oscillation

• DOI: 10.1523/jneurosci.3375-10.2011
• Publication Date: 2011-01-12T17:23:23Z
• Authors: Andrea Slézia; Balázs Hangya; István Ulbert; László Acsády
• Keywords: Oscillation (cell signaling); Premovement neuronal activity; Cortical neurons

The exact timing of cortical afferent activity is instrumental for the correct coding and retrieval internal external stimuli. Thalamocortical inputs represent most significant subcortical pathway to cortex, but precise temporal variability thalamocortical not known. To examine this question, we studied phase thalamic action potentials relative oscillations established correlations among phase, nuclear location neurons, frequency activity. depended on slow oscillation both long (minutes) short (single wave) time scales. Faster waves were accompanied by advancement in cases. neurons located different nuclei fired at significantly phases active a similar spindle oscillations. Different displayed distinct burst patterns. Bursts with higher number progressive nucleus-specific manner. Thalamic along borders characterized mixed properties. Our data demonstrate that relationship between fixed displays dynamic changes during oscillatory depends cells ongoing network pattern. This output its coupling can enable actively participate signals.