Dynamics of Suppression in Macaque Primary Visual Cortex

• DOI: 10.1523/jneurosci.5542-06.2006
• Publication Date: 2006-05-03T20:24:13Z
• Authors: Matthew A. Smith; Wyeth Bair; J. Anthony Movshon
• Keywords: Surround suppression; Stimulus (psychology)

The response of a neuron in primary visual cortex (V1) to an optimal stimulus its classical receptive field (CRF) can be reduced by the presence orthogonal mask, phenomenon known as cross-orientation suppression. parallel outside CRF have similar effect, this case surround We used novel probe time course suppression and found that it is very fast, starting even before excitatory stimuli. However, occurs with some delay after offset response, considered measure earliest signals reach CRF. also examined presented begins substantially earlier than measured same cells. Together, these findings suggest attributable either direct feedforward signal paths V1 neurons or circuit involving fast local interneurons within V1. Feedback from higher cortical areas implicated suppression, but our results make implausible mechanism for conclude inside occur through different mechanisms.