Effectiveness Of Using Fermented Herbal Preparation In Complex Therapy Of Periodontitis Developed As An Orthodontic Treatment Complication

Proinflammatory cytokine
DOI: 10.15275/rusomj.2021.0425 Publication Date: 2022-01-21T10:08:10Z
ABSTRACT
Objective — to study the effectiveness of topical application standardized fermented papaya gel (SFPG) in complex therapy moderate chronic periodontitis developed as an orthodontic treatment complication. Material and Methods Our involved 50 patients with a severity against background fixed appliance. Periodontitis has long-term consequence Orthodontic was carried out metal ligature braces. The were divided into two groups: Group 1 conventional supplemented by SFPG applications on gums for 15 minutes daily during 14 days; 2 alone. concentration proinflammatory anti-inflammatory cytokines periodontal pockets determined using solid-phase type enzyme immunoassay (Vector-Best test system, Russia). nitrite/nitrate content pocket fluid spectrophotometrically Griess reagent kit, following manufacturer’s instructions (Sigma-Aldrich, USA). Results Patients receiving SFGP exhibited reduction inflammation, manifested decreased gum bleeding, swelling, hyperemia, exudate from pockets. We observed restoration balance (IL-1β, IL-6) interleukin (IL-10), content. Conclusion Clinical natural herbal preparations may be associated its antioxidant antimicrobial properties.
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