Cytonuclear Genic Incompatibilities Cause Increased Mortality in Male F2 Hybrids ofNasonia giraultiandN. vitripennis

• DOI: 10.1534/genetics.107.080523
• Publication Date: 2008-01-17T22:53:09Z
• Authors: Oliver Niehuis; Andrea K Judson; Jürgen Gadau
• Keywords: Nasonia vitripennis

The haplodiploid wasp genus Nasonia is a promising model for studying the evolution of genic incompatibilities due to existence interfertile species and haploid males. latter allows significantly reducing sample size required detect map recessive dysfunctional interactions. We exploited these features study genetics intrinsic hybrid inviability in male F2 hybrids giraulti N. vitripennis. Analyzing marker segregation 225 embryos, we inferred linkage with 38 framework markers. markers were tested transmission ratio distortion (MTRD) interchromosomal disequilibrium populations embryonic adult hybrids. found evidence four distorting loci (TRDL). Three TRDL showed deficit allele vitripennis cytoplasm. A separate exhibited deficiency ascribe observed MTRD cytonuclear causing differential mortality during development since embryos did not show MTRD. identified cytoplasm account most this cross. high rate cannot be explained by single alone, however.