Clinical Features and Anaphylaxis in Children With Cold Urticaria

• DOI: 10.1542/peds.113.4.e313
• Publication Date: 2004-08-14T00:53:04Z
• Authors: Abdullah A. Alangari; Frank J. Twarog; Mei-Chiung Shih; Lynda C. Schneider
• Keywords: Hypersensitivity, Immediate; Male; Adolescent; Urticaria; Infant; 3. Good health; Cold Temperature; 03 medical and health sciences; 0302 clinical medicine; Risk Factors; Child, Preschool; Humans; Female; Age of Onset; Child; Anaphylaxis; Skin Tests

To characterize the features of cold urticaria in children, with particular focus on systemic reactions, because little pediatric data are available.Chart reviews 30 children <18 years old who were evaluated past 3 at Children's Hospital Allergy Program (Boston, MA) and a private allergy practice. Demographic, diagnostic, therapeutic collected. Telephone interviews patients and/or their parents performed to obtain follow-up data.Our showed that mean median ages onset approximately 7 years. No secondary causes found. One third had anaphylactic reactions. These reactions could not be predicted based available variables. Patients negative cold-stimulation test (ice-cube challenge) 10 minutes similar symptoms response antihistamines as those positive ice-cube-challenge test. In addition, our group strikingly high rate asthma (46.7%) allergic rhinitis (50%). The family history atopic diseases was even higher (89.3%).Cold occurs may associated anaphylaxis. series, no All should cautioned regarding risk anaphylaxis provided an epinephrine autoinjector.