THE INCIDENCE OF CONGENITAL MALFORMATIONS: A STUDY OF 5,964 PREGNANCIES

• DOI: 10.1542/peds.14.5.505
• Publication Date: 2021-12-11T08:02:13Z
• Authors: RUSTIN MCINTOSH; KATHARINE K. MERRITT; MARY R. RICHARDS; MARY H. SAMUELS; MARJORIE T. BELLOWS
• Keywords: Congenital malformations; Neonatal Mortality; Neonatal death

I. The plan is described of a prospective study the outcome 5,964 pregnancies, with special emphasis on relationship factors in fetal environment to incidence abortions, stillbirths, neonatal mortality and congenital malformations. II. Data are presented overall malformations according sex, race, weight at delivery, maternal age order birth. A. among 5,739 products conception weighing over 500 grams was 7.5%. rate 7.0% infants born alive surviving period, 13.6% antepartum deaths, 23.3% intrapartum 29.6% deaths 70.6% occurring between ages one 12 months. B. following relationships rates live-born period were found. 1. males (8.4%) half again as high females (5.5%). 2. Non-white had higher (7.8%) than white (6.3%). 3. Infants 2,500 or less proportion defects (9.7%) did those (6.7%), although this difference occurred entirely females. 4. Maternal no effect 5. White lower birth (5.3%) orders (8.2%). No observed non-white infants. III. A system classification discussed. Incidence by organ groups presented. Less one-half found suspected noted Malformations musculo-skeletal skin more frequent other systems. directly related problems diagnosis. C. Of malformed infants, 14.8% malformation 9.1% involved. stillbirths 66.0% 51.1%