Steroid Effects on the Course of Abdominal Pain in Children With Henoch-Schonlein Purpura

• DOI: 10.1542/peds.79.6.1018
• Publication Date: 2021-12-11T01:02:48Z
• Authors: NORMAN D. ROSENBLUM; HARLAND S. WINTER
• Keywords: 03 medical and health sciences; Time Factors; 0302 clinical medicine; IgA Vasculitis; Abdomen; Humans; Pain; Prednisone; Child; Retrospective Studies; 3. Good health

Henoch-Schonlein purpura is a systemic vasculitis of unknown cause that is characterized primarily by abdominal pain, arthritis, and purpuric skin lesions. Abdominal pain is the most common gastrointestinal symptom, but intestinal bleeding and intussusception may occur. Previous studies have supported the use of steroids in managing the abdominal pain of Henoch-Schonlein purpura.1,2 Because there are no controlled trials using steroids in this disease, their value in affecting the intestinal lesions of Henoch-Schonlein purpura remains unknown. The purpose of this retrospective study was to assess the effect of corticosteroids on the outcome of abdominal pain in children with Henoch-Schonlein purpura. PATIENTS AND METHODS