A diagnostic challenge in clinical laboratory: Misidentification of Neisseria subflava as Neisseria meningitidis by MALDI-TOF MS

• DOI: 10.1556/030.2020.01039
• Publication Date: 2020-03-30T08:25:02Z
• Authors: Tugce Unalan-Alti...; Alper Karagoz; Gulsen Hazirolan
• Keywords: Neisseria; Clinical Microbiology

Abstract MALDI-TOF MS provides fast, easy to perform and cost-effective diagnosis in clinical microbiology laboratories, however some cases results of should be confirmed with additional tests. This confirmation is especially important for causes life-threatening infections like Neisseria meningitidis . In our laboratory, three isolates were identified as N. by Bruker MALDI Biotyper (BD, USA) between April 2018 March 2019 from specimens blood, sputum, urine. 16S rRNA sequencing was performed further investigation. Two the subflava only one sequencing. These show that not always reliable microbiologists confirm these Also, correlations determined. Accurate identification this microorganism very because necessity prophylactic antimicrobial usage biosafety precautions. Enlarged databases species are needed overcome problem.