Therapy of secondary cutaneous toxicity as a result of radioterapic treatment, with a sH oligopeptide-1 cream based (epidermal growth factor-egf): a pilot study

• DOI: 10.15568/am.2018.804.or04
• Publication Date: 2018-10-30T14:09:16Z
• Authors: Antonio Luis Sera...; Ana Carreras-Sosp...; ; Carla López-Jimeno; ; Vanessa Hijano-Be...; ; Mariano Viedma-Pa...; ; Gabriella Russo; ; Teo Mayayo-Falo; ; Fernando Martínez...; ; María Fernández-R...
• Keywords: Radiodermatitis

Acute dermatitis is very common in patients being treated for breast, brain, neck and skin tumours, due to the high doses of radiation administered, it can affect up 95% patients.. These effects decrease patients’ quality lifeThe objective this study evaluate effectiveness Radio Cream® by Inves Biofarm as a prophylactic measure against radiodermatitis. We recruited twenty requiring radiotherapy, with between 42.72 Gy 70 Gy. The cream was applied, twice day. Skin toxicity evaluated National Cancer Institute Common Terminology Criteria Adverse Events (NCI CTCAE), which assess acute injuries on scale 0 4. At end treatment, percentages 5%, 65% 30% were observed grades 0, 1, 2 respectively; no cases grade 3 or 4 found. When treatment finished, 70% had pruritus 1. average score 8.38 1 10. consider that has proved be valid option preventing It prevent delay appearance cutaneous toxicity, helping maintain life making possible complete radiotherapy at prescribed doses.