Seroprevalence of SARS-CoV-2 Among Frontline Health Care Personnel in a Multistate Hospital Network — 13 Academic Medical Centers, April–June 2020

• DOI: 10.15585/mmwr.mm6935e2
• Publication Date: 2020-08-31T16:35:37Z
• Authors: Wesley H. Self; Mark W. Tenforde; William B. Stubbl...; Leora R. Feldstein; Jay S. Steingrub; Nathan I. Shapiro; Adit A. Ginde; Matthew E. Prekker; Samuel M. Brown; Ithan D. Peltan; Michelle N. Gong; Michael S. Aboodi; Akram Khan; Matthew C. Exline; D. Clark Files; Kevin W. Gibbs; Christopher J. Li...; Todd. W. Rice; Ian D. Jones; Natasha Halasa; H. Keipp Talbot; Carlos G. Grijalva; Jonathan D. Casey; David N. Hager; Nida Qadir; Daniel J. Henning; Melissa M. Coughlin; Jarad Schiffer; Vera Semenova; Han Li; Natalie J. Thornburg; Manish M. Patel; ; ; ; Adrienne Baughman; Kimberly W. Hart; Robert McClellan; Rendie McHenry; Jakea Johnson; Andrea Fletcher; Curtis Rich; Kemberlyne Cordero; Lori Kozikowski; Lesley De Souza; Sarah Romain; Scott Ouellette; Andres Santana; Sherell Thornton-...; Michelle Howell; Jennifer Peers; Shelby Shelton; Lani Finck; Kirsten Soules; Michael Klausner; Ximena Calderon-M...; Heidi L. Erickson; Audrey Hendrickson; Jamie Stang; Ellen Maruggi; Alex Dunn; Eddie Stenehjem; Intermountain Hea...; Valerie Aston; Mikaele Bown; Michelle Matheu; Rilee Smith; Olivia Krol; Andrew Salar; Oregon Health; Makrina Kamel; Oregon Health; Kelly Nguyen; Peter Huynh; Sarah Karow; Michelle Bright; Holly Bookless; Sandy Mullins; Kelly Neidert; Dina McGowan; Elizabeth Cassandra; Emily Brown; Claire Carlin; Trina Wemlinger; Breona Edwards; Lori Flores; Mary LaRose; Kathie J. Ferbas; Rachel Martin-Blais; Grace M. Aldrovandi; Olivia Thompson; Sakshi Sehgal; ; Mohammed Ata Ur R...; Lisa Mills; Sandra N. Lester; Brandi Freeman; Bailey Alston; Muyiwa Ategbole; Peter Browning; Li Cronin; Ebenezer David; Rita Desai; Monica Epperson; Yamini Gorantla; Tao Jia; Pete Maniatis; Kristina Ortiz; So Hee Park; Palak Patel; Yunlong Qin; Heather Tatum; Briana Zellner
• Keywords: Seroprevalence; 2019-20 coronavirus outbreak; Sars virus

Health care personnel (HCP) caring for patients with coronavirus disease 2019 (COVID-19) might be at high risk contracting SARS-CoV-2, the virus that causes COVID-19. Understanding prevalence of and factors associated SARS-CoV-2 infection among frontline HCP who COVID-19 are important protecting both their patients. During April 3-June 19, 2020, serum specimens were collected from a convenience sample worked 13 geographically diverse academic medical centers in United States, tested antibodies to SARS-CoV-2. Participants asked about potential symptoms experienced since February 1, previous testing acute infection, use personal protective equipment (PPE) past week. Among 3,248 participants, 194 (6.0%) had positive test results antibodies. Seroprevalence by hospital ranged 0.8% 31.2% (median = 3.6%). seropositive 56 (29%) reported no 86 (44%) did not believe they previously COVID-19, 133 (69%) report diagnosis. was lower always wearing face covering (defined this study as surgical mask, N95 respirator, or powered air purifying respirator [PAPR]) while (5.6%), compared those (9.0%) (p 0.012). Consistent persons general population many asymptomatic minimally symptomatic during unrecognized. Enhanced screening, including frequent HCP, universal coverings hospitals two strategies could reduce transmission.