Measles Update — United States, January 1–April 17, 2025

• DOI: 10.15585/mmwr.mm7414a1
• Publication Date: 2025-04-24T12:24:41Z
• Authors: Adria D. Mathis; Kelley Raines; Thomas D. Filardo; Nicole Wiley; Jessica Leung; Paul A. Rota; Diana Martinez; Saroj Rai; Varun Shetty; Nora Holzinger; Emma Stanislawski; Demetre C. Daskal...; Kevin Chatham-Ste...; Manisha Patel; David Sugerman

A multistate measles outbreak, predominantly affecting members of close-knit communities with low vaccination coverage in New Mexico, Oklahoma, and Texas began January 2025. As April 17, a total 800 cases have been reported the United States 2025; 654 (82%) associated ongoing outbreak. These represent an approximately 180% increase over 285 during all 2024, second highest annual case count 25 years. Overall, 771 (96%) patients unvaccinated or had unknown status (77% were unvaccinated, 14% when excluding 590 by Texas, which requires explicit consent law [i.e., opt-in] to enroll Immunization Registry), 85 (11%) hospitalized, three died. Among 48 (6%) internationally imported cases, 44 (92%) occurred among U.S. residents. Endemic was declared eliminated 2000 as direct result high 2-dose childhood measles, mumps, rubella (MMR) vaccine. However, outbreaks continue occur travelers return while they are infectious; larger typically follow importation into coverage. Nationally, risk for widespread transmission remains because population-level immunity. To prepare prevent outbreaks, public health departments should working trusted community messengers on culturally competent engagement, education, efforts, other infection prevention approaches (e.g., isolation, contact monitoring, post-exposure prophylaxis) coordinating care facilities schools. Increasing national local MMR is essential preventing outbreaks.