Introduction to Biochemistry: Protein Structure and Enzyme Basics

• DOI: 10.15766/mep_2374-8265.8122
• Publication Date: 2014-10-01T14:34:29Z
• Authors: Daniel Eskenazi; David Acosta
• Keywords: Coursework

OPEN ACCESSMay 11, 2010Introduction to Biochemistry: Protein Structure and Enzyme Basics Daniel Eskenazi, PhD(c), David Acosta, MD PhD(c) University of Washington School Medicine , https://doi.org/10.15766/mep_2374-8265.8122 SectionsAbout ToolsDownload Citations ShareFacebookTwitterEmail Abstract Introduction: The purpose this learner-directed, stand-alone tutorial is teach learners how basic science building blocks relate clinical scenarios in the field biochemistry. goal for them retain information regarding protein structure enzyme basics understand it ultimately relates physiology medicine. Specifically, students will build upon chemical physical principles biochemistry context Gibbs free energy, activation energy plots, reaction rate analysis. Further, connect knowledge clinically by relating structural changes disease sickle cell anemia metabolic phenylketonuria. Review questions at end provide opportunity practice drawing structures test their knowledge. Methods: designed be completed over one or two sessions, perhaps dividing up into session another session. Motivated able find online as an tool both aid coursework preparation health school entrance exams. Instructors may review materials supplement lessons incorporate further discussion topics brought tutorial. slides themselves used guides expand fit existing syllabi. Results: This based on Summer Medical & Dental Education Program (SMDEP) 2 years, experienced more than 50 students. Effectiveness was assessed via final examination containing multiple choice well short-answer structures; all motivated excelled exam with some performing outstandingly (> 95% score a multiple-choice, 10 question exam, covering material six other lessons). Student enthusiasm course evaluated questionnaire; scored highest SMDEP components 2009. Discussion: significance work that serve any undergraduate providing free, open-access, access professional Educational Objectives By module, learner to: Appreciate underlying proteins dictates functions relation human disease.Build analysis.Gain phenylketonuria.Review Sign latest publications from MedEdPORTAL Add your email below FILES INCLUDEDReferencesRelatedDetails INCLUDED Included publication: Instructor's Guide.docx Tutorial.ppsx Tutorial Instructors.pptx To view publication components, extract (i.e., unzip) downloaded .zip file. Download editor's noteThis contain technology display format no longer use. CitationEskenazi D, Acosta D. Introduction Basics. MedEdPORTAL. 2010;6:8122. Copyright Permissions© 2010 Eskenazi Acosta. open-access distributed under terms Creative Commons Attribution-NonCommercial-Share Alike license.KeywordsGibbs Free EnergySickle Cell DiseaseCompetitive InhibitionEnzymesProteinPKUActivation EnergyAmino AcidNon-competitive InhibitionPhenylketonuria Disclosures None report. Funding/Support Loading ...