Hepatitis A seroprevalence among special populations in the Rio de Janeiro Metropolitan Area, Brazil

• DOI: 10.1590/0102-311xen075522
• Publication Date: 2024-05-02T20:22:33Z
• Authors: Flavio de Carvalho; Luciana Gomes Ped...; Margaret Catoia V...; Mari Tuyama; Danusa Ferreira C...; Ananza Taina da S...; Alberto dos Santo...; Marcellus Dias da...; José Cerbino-Neto; Pedro Emmanuel Al...
• Keywords: Seroprevalence

The objectives were to estimate hepatitis A virus seroprevalence in subjects attending a travel medicine and immunization clinic Rio de Janeiro, Brazil, develop prediction model for seroprevalence. This retrospective research included individuals sequentially from April 2011 June 2019 at special population with an anti-hepatitis IgG chemiluminescence result. Participants' data verified via electronic medical records. Data split into development validation set taking 2018 as the date break. cross-validated elastic generalized linear binomial distribution was performed. In total, 2,944 analyzed. Hepatitis overall 67.8%. Health professionals, travelers, those who had contact immunocompromised lower (40%-55%), whereas chronic conditions (heart, lung, liver) ranged 89% 94%. retained predictors final sex, age, year of birth, HIV/AIDS, spleen dysfunction, transplant candidates, household communicators, cancer-related immunosuppression, health care professionals. Area under curve 0.836 maximum error 0.051. Users can make predictions following calculator: https://pedrobrasil.shinyapps.io/INDWELL/. groups should be evaluated more carefully regarding need vaccination even when they seek clinics other purposes.