Implantation of autologous fat globules in localized scleroderma and idiopathic lipoatrophy - report of five patients

• DOI: 10.1590/abd1806-4841.20132115
• Publication Date: 2014-01-30T19:47:14Z
• Authors: Tiago Pina Zanelato; Giovana Marquesini; Paula Tavares Colpas; Renata Ferreira M...; Aparecida Machado...
• Keywords: Adult; Male; Adolescent; Lipodystrophy; Subcutaneous Fat; Esclerodermia localizada; Case Report; Dermatology; Transplantation, Autologous; Scleroderma, Localized; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Facial Hemiatrophy; Humans; Subcutaneous fat; 3. Good health; Treatment Outcome; RL1-803; Face; Atrofia; Gordura subcutânea; Female; Atrophy; Scleroderma, localized

A large number of diseases may cause Atrophic skin disorders are caused by a large number of diseases, some of them idiopathic and others inflammatory, in which there is loss of volume of body segments. Localized scleroderma is a rare inflammatory dermatosis, manifested by atrophic skin and subcutaneous tissue alterations. Lipoatrophy may be genetically inherited or acquired as a result of panniculitis, HIV infections or aging. Many treatments have been proposed. Results vary in the acute inflammatory phase and are scarce when sclerosis and atrophy have already been established. This article describes four cases of localized facial scleroderma and one of facial idiopathic lipoatrophy treated with implantation of autologous fat globules extracted from the infragluteal groove, without utilization of cannula aspiration, with lasting results.