Diagnostic and therapeutic guidelines for plaque psoriasis - Brazilian Society of Dermatology

• DOI: 10.1590/abd1806-4841.2019940211
• Publication Date: 2019-06-01T19:49:52Z
• Authors: Marcelo Arnone; Maria Denise Fons...; André Vicente Est...; Wanderley Marques...; Aline Lopes Bressan; Andrea Machado Co...; Aripuanã Cobério ...; Cacilda da Silva ...; Daniel Holthausen...; Maria Cecília de ...; Maria de Fátima S...; Jane Marcy Neffá; Luciana Cristina ...; Luna Azulay-Abulafia; Paulo Antônio Old...; Renata Ferreira M...; Ricardo Romiti; Tatiana Jerez Jaime
• Keywords: Male; Practice guidelines as topic; Time Factors; Calcineurin Inhibitors; Comorbidity; Dermatology; Severity of Illness Index; 03 medical and health sciences; 0302 clinical medicine; Adrenal Cortex Hormones; Humans; Psoriasis; Biological therapy; Vitamin D; Societies, Medical; Antibodies, Monoclonal; Anthralin; Phototherapy; 3. Good health; Drug Combinations; Methotrexate; RL1-803; Cyclosporine; Female; Dermatologic Agents; Brazil

Psoriasis is a chronic inflammatory disease that affects 1.3% of the Brazilian population. The most common clinical manifestations are erythematous, scaling lesions that affect both genders and can occur on any anatomical site, preferentially involving the knees, elbows, scalp and genitals. Besides the impact on the quality of life, the systemic nature of the disease makes psoriasis an independent risk factor for cardiovascular disease, especially in young patients with severe disease. By an initiative of the Brazilian Society of Dermatology, dermatologists with renowned clinical experience in the management of psoriasis were invited to form a work group that, in a partnership with the Brazilian Medical Association, dedicated themselves to create the Plaque Psoriasis Diagnostic and Treatment Guidelines. The relevant issues for the diagnosis (evaluation of severity and comorbidities) and treatment of plaque psoriasis were defined. The issues generated a search strategy in the Medline-PubMed database up to July 2018. Subsequently, the answers to the questions of the recommendations were devised, and each reference selected presented the respective level of recommendation and strength of scientific evidence. The final recommendations for making up the final text were worded by the coordinators.