Evaluation of Salmonella-Lytic Properties of Bacteriophages Isolated from Commercial Broiler Houses

• DOI: 10.1637/8017-050807-resnote
• Publication Date: 2008-03-26T19:17:58Z
• Authors: J. P. Higgins; R. L. Andreatti F...; S. E. Higgins; A. D. Wolfenden; G. Tellez; B. M. Hargis
• Keywords: Lytic cycle; Isolation; Phage typing; Lysogenic cycle; Phage therapy

Because of recent interest in bacteriophage therapy poultry, information regarding the interaction bacteriophages and potential host bacteria environment should be collected. The present studies were initiated with a rather typical commercial broiler integrator within south-central United States to examine environmental Salmonella levels two complexes, attempt isolate Salmonella-lytic bacteriophages, elucidate possible reason for differing apparent prevalence. Significantly (P < 0.05) less was isolated from houses complex 1 (15/44 [34%] Salmonella-positive drag swabs) as compared 2 (22/24 [92%]). A total seven environments, single Salmonella-negative house. During initial isolation, individual did not replicate same environment, lysis additional hosts relied on high numbers present. This suggests that presence these house had little no effect Salmonella. study highlights need find sources, more effective isolation methods, innovative approaches using treat enteric disease.