FINDING OF CELIAC DISEASE DURING THE STUDY OF KIMURA DISEASE IN A CAUCASIAN MALE

• DOI: 10.17235/reed.2024.10853/2024
• Publication Date: 2024-11-07T10:25:52Z
• Authors: Elena Pablo-Martín; Laura Corvo-Félix; Marta Rodríguez G...; Andrea Beatriz Ji...; Luis Figuero-Pérez; María Luisa Pérez...; Emilio Fonseca-Sá...
• Keywords: Kimura's disease

We present the case of a 27-year-old man, with no previous diseases, who was referred to Department Otorhinolaryngology in May 2023 for 2-cm right submandibular lymphadenopathy two month's evolution. He did not report fever or night sweats, and oral genital ulcers were observed. presented eosinophilia analysis performed maculopapular exanthema on left leg malleolus areas, which initially treated topical antibiotic corticosteroids. A soft tissue ultrasound revealed laterocervical lymphadenopathies at levels I II. Given suspicion primary hematological tumor, PET-CT scan conducted complete study, hypermetabolic bilateral lymphadenopaties. In June 2023, programmed cervicotomy conducted, excision main Ib region, showed histological result reactive lymphadenitis intense eosinophilia, vascular proliferation, fibrosis. These findings suggest Kimura disease as first possibility. Due sporadic episodes choking that associated specific food, persistent elevated IgE peripheral blood tests, skin alterations, study completed gastroscopy rule out presence eosinophilic esophagitis, erosive duodenitis, villous shortening increased lymphoplasmacytic cellularity lamina propria, consistent celiac disease, afterwards confirmed positive anti-endomysial transglutaminase antibodies, HLA-DQ8 homozygosis genetic study. The patient started systemic treatment corticosteroids gluten-free diet, he continues take present.