Dynamics of the content of immunoglobulin G to severe acute respiratory syndrome-2 in convalescents who have had a new coronavirus infection

• DOI: 10.17816/brmma108612
• Publication Date: 2023-01-03T23:50:01Z
• Authors: Ivan V. Fateev; Timur V. SchÖfer; Sergey V. Chepur; Evgeniy V. Ivchenko; Timur I. Minnullin; Alla A. Shubina; Alexander V. Step...
• Keywords: Sore throat; Convalescence; Throat; Coronavirus

The study investigated the dynamics of class G immunoglobulins to severe acute respiratory syndrome-2 coronavirus in blood serum convalescents who had a new infection for 6 months after polymerase chain reaction conversion. Among most common symptoms, 30 (73.8%) an increase body temperature 38C, 32 (83.3%) asthenia, 21 (59.5%) cough, 29 perversion or loss sense smell, pain, and throat discomfort. duration symptoms varied from 34 days weeks. Within month end disease period, 8 (20%) patients decrease working capacity, 13 (33%) difficulty breathing, 9 (22%) 4 (10%) pain sore throat. During syndrome 2 infection, virus activates innate adaptive immunity, resulting formation specific pathogens. After leveling clinical manifestations, were detected majority (79%90%) during first months, starting day 14 onset with predominantly high ( 10 conl. units) positivity coefficient. Moreover, this pattern occurred both men women; however, some studies, levels coefficient began by fifth follow-up sometimes at earlier time (2 months). Perhaps, is due different functional activities immune system each convalescent, infecting dose pathogen, peculiarities its interaction macroorganism system. Nevertheless, identified do not yet indicate probability reinfection same pathogen. protective titer antibodies has be further.