Assessment of a new "DS-EIA-HIV-AB-TERM" assay to determine the probable time of infection with human immunodeficiency virus-1 (HIV-1)

• DOI: 10.17816/eid40863
• Publication Date: 2021-04-07T18:44:33Z
• Authors: Yu. E Zagryadskaya; D. A Neshumaev; Yu. A Kokotyukha; E. M Meyrmanova; I. A Olkhovskiy; V. F Puzyrev; A. N Burkov; T. I Ulanova
• Keywords: Seroconversion; Hiv test

The epidemiological situation for HIV infection in Russia remains to be extremely stringent, which requires a search new, more efficient and cost-effective solutions aimed at countering the epidemic. inclusion of laboratory studies with use test system determination remoteness routine surveillance practices will permit determine frequency occurrence early cases infections among newly diagnosed HIV-positive persons. analysis this criterion population level help objectively evaluate effectiveness prevention, control activities carried out particular area. increase objectivity time elapsed from moment HIV-1 DSEIA-HIV-Ab-TERM provides opportunity obtained results investigation purpose accurate complete identification contact probable period may also required solving question on prescription antiretroviral therapy as complementary study monitoring drug resistance. aim work was new DS-EIAHIV-Ab-TERM likely timing infection. There were studied serum samples (plasma) blood HIV-infected persons epidemiologically established (n = 281) commercial seroconversion panels. Results performed showed that probability correct detection individuals most fact 95%, panels - 100%. data demonstrated high efficacy DS-“EIAHIV-Ab-TERM” human immunodeficiency virus type 1, combination speed simplicity procedure allows recommend it practice.