Chronic viral mixt-hepatitis: current clinical and epidemiological aspects

• DOI: 10.17816/eid40876
• Publication Date: 2021-04-07T18:44:33Z
• Authors: M. G Avdeeva; V. N Gorodin; M. I Kulbuzheva; L. P Blazhnaya; S. R Hasnudinova; E. I Kolodko
• Keywords: Viral Hepatitis; Hepatitis B; Hepatitis C; Concomitant

Objective: Improvement of the diagnosis and prognosis liver disease viral etiology based on analysis clinical epidemiological characteristics course outcome mixt-hepatitis. Materials methods There are presented results retrospective study 106 patients with chronic mixt-hepatitis (study group), which were under medical observation for a period from two to five years between 2010 2014. The comparison group was consisted 1,913 hepatitis C. Results discussion morbidity in majority cases is registered among socially active groups young middle age persons, more common males. Frequent risk factors artificial factor (55%), intravenous drug usage (25%), tattooing (19%). Typical concomitant illnesses diseases gastrointestinal tract endocrine system. Chronic mainly caused by combination HCV HBV, + HBV HDV also. replication noted 64% cases, - 58%, 20%. Transformation into cirrhosis C+B+D recorded 25% C+B 7.1%. In patients, without transformation seen 36%. case alone, rate 25%, while isolated 14%. mixt-infection C+B, development within subgroup simultaneous viruses 9% cases. An replication, general less often, led 6% Conclusions. Simultaneous than one type virus promotes cirrhosis, greater extent, HDV, monoreplication order prevent further progression pathological process it recommended well-timed causal treatment account predominant replication.