Lobular carcinomas of the breast: cytological diagnostics

• DOI: 10.17816/onco197446
• Publication Date: 2023-05-14T19:41:54Z
• Authors: Ol’ga G. Grigoruk; Tat’jana A. Moskvina; Larisa M. Михайл...; Tat’jana V. Sinkina; Igor’ V. Vihljanov
• Keywords: Lobular carcinoma; Invasive lobular carcinoma; Breast carcinoma; Cytopathology

AIMS: To estimate potentialities of cytological diagnostics different types lobular carcinomas the breast while outpatient examination.
 MATERIALS AND METHODS: The data investigations 444 patients with carcinoma, which were detected by fine-needle aspiration biopsy, studied. Traditional diagnostics, as well liquid-based technique preparation patterns used, staining according to Pappenheim and Papanicolaou methods. A standard protocol for immunocytochemical reactions was used.
 RESULTS: Lobular carcinoma in 15 patients. Types verified method retrospectively identified.
 Classical, solid tubular (n=7,46.7%; n=5,33.3%; n=1,6.7%) differed from unspecified carcinomas. In classical type, vacuoles a target-like inclusion (probably drop mucin) significant feature. absence complexes large number separately located similar tumor cells noticed. type distinguished presence structures. helps differentiate using an reaction E-cadherin.
 CONCLUSION: results study indicate that are 3.4% all Taking into consideration differences prognosis, it is important between ductal at level this deciding treatment strategy choice.