Extensive liver resection with preoperative chemotherapy for colorectal metastases with high risk of complications

• DOI: 10.17816/onco40021
• Publication Date: 2023-12-17T12:18:17Z
• Authors: Yu. I Patyutko; K. G Mamontov; A. G Kotelnikov; A. A Ponomarenko; A. F Lazarev

Objective: to study influence of preoperative chemotherapy on postoperative complications rate. Material and methods: an analysis 455 cases extensive liver resection. 229 (56%) patients didn’t receive neoadjuvant chemotherapy, 176 (44%) - received chemotherapy. 216 (53%) had bilobar lesions, 156 (39%) multiple metastases, 168 (42%) synchronous 237 (58%) metachronous metastases. 60 (15%) in addition been resected for extrahepatic Results: bevacizumab inckusion regional did not lead increase complication Conclusion: Postoperative rate significantly differ all groups treatment, regardless resection volume. Extension from standard hepatectomy extensive, leads statistically significant acute hepatic failure. Acute failure takes the first place among (21%).