METABOLIC PROFILE OF YOUNG WOMEN IN EARLY PREGNANCY AND AFTER INDUCED ABORTION

• DOI: 10.17816/rfd2014133-36
• Publication Date: 2016-07-21T08:26:36Z
• Authors: O V Panova; A M Kulikov
• Keywords: 03 medical and health sciences; 0302 clinical medicine; 3. Good health

The metabolic profile was estimated in young pregnant women 15-19 years old as the level of substances of low and middle molecular mass in blood serum, red blood cells and urine. The assessment was provided in the early period before the 12th week of gestation and after the medical abortion. Metabolic changes were indicated in 59,5% of patients. The endogenous intoxication was found in one third of patients (30,5%). The activation of metabolic processes during the fetal growth, the presence of toxicosis and acute inflammation diseases can be considered as possible reasons of the endogenous intoxication. Pregnancy interruption didn't lead to disappearance of endogenous intoxication and metabolic damages. On the contrary in a week after induced abortion the metabolic profile in a half of patients worsened due to accumulation of substances of catabolic origin in the biological environment. Postponed adverse metabolic changes were also found. The level of substances of low and middle molecular mass approached to normal in a month after abortion. There is an evidence that interruption of pregnancy by the means of surgical abortion turned out to be a high-powered factor for the metabolic disorders of different degree of manifestation.