Gorham–Stout disease started with recurrent bilateral exudative pleuritis: case description and literature review

• DOI: 10.17816/rfd625565
• Publication Date: 2024-03-31T16:51:44Z
• Authors: Olga M. Lesnyak; Vadim G. Pischik; Olga N. Tkach; Elena S. Kunitsina
• Keywords: Pleurisy

Gorham–Stout disease is an extremely rare skeletal disorder of unknown etiology manifested by multiple foci osteolysis (“vanishing bone disease”) and lymphangiomatosis. Osteolysis can occur in any part the skeleton (skull, facial skeleton, ribs, clavicula, spine, pelvic bones, bones upper lower extremities). Approximately half patients develop pleural effusion, accompanied respiratory abnormalities. We describe a case Gorham-Stout with recurrent bilateral exudative pleuritis as first most prominent sign, while lesions at vertebral bodies, ribs sternum proceeded without active complaints were accidental finding during chest computer tomography. Timely diagnosis depends on awareness doctors various specialties careful reading imaging results.