Characterization of SPECTRUM Variable Nicotine Research Cigarettes

• DOI: 10.18001/trs.2.2.1
• Publication Date: 2016-03-25T02:17:57Z
• Authors: Patricia Richter; R. Steven Pappas; Roberto Bravo; Joeseph G. Lisko; Maria Damian; Nathalie Gonzales...; Naudia Gray; Lisa M. Keong; Jacob B. Kimbrell; Peter Kuklenyik; Tamela S. Lawler; Grace E. Lee; Magaly Mendez; Jose Perez; Shakia Smith; Hang Tran; Robert Tyx; Clifford H. Watson
• Keywords: Broad spectrum; Nicotine dependence

To provide researchers an extensive characterization of the SPECTRUM variable nicotine research cigarettes.Data on cigarette physical properties, content, harmful and potentially constituents in tobacco filler was compiled.Data concentrations menthol, minor alkaloids, tobacco-specific nitrosamines, polycyclic aromatic hydrocarbons, ammonia, toxic metals for all available varieties Spectrum cigarettes are provided. The similarity chemistry properties to commercial renders them acceptable use behavioral studies. Baseline information products, particularly constituent levels such as alkaloids that fall outside typical ranges reported commercial, with opportunity monitor smoking behavior identify biomarkers will inform efforts understand role creating sustaining addiction.Well characterized suitable human consumption important tool clinical studies investigating physiological impacts delivering various nicotine, impact reduced addiction, relationship between dose behavior.