Condition of the Right Heart in Patients With COVID-19‑Associated Pneumonia: Follow-Up During Hospitalization

• DOI: 10.18087/cardio.2023.8.n2092
• Publication Date: 2023-09-12T06:52:12Z
• Authors: N. G. Poteshkina; N. S. Krylova; A. A. Karasev; T. A. Nikitina; I. P. Beloglazova; E. A. Kovalevskaya; V. V. Parshin; M. A. Lysenko; A. M. Ibragimova; V. N. Smorshchok
• Keywords: Ground-glass opacity; Viral Pneumonia; Stepwise regression; 2019-20 coronavirus outbreak

Aim Dynamic assessment of the right heart in patients with COVID-19-associated pneumonia different severity during regression systemic inflammatory response (SIR).Material an methods This single-center prospective study included 46 novel coronavirus infection COVID-19 and viral according to chest multispiral computed tomography (CT). Laboratory echocardiographic examinations were performed.Results Based on results evaluation Clinical Condition Scale (CCS-COVID), divided into two groups: group A, a score from 6 9 B, 10 14. The both groups evaluated twice: day 10±2.5 onset symptoms (groups A10 B10, respectively) again 17±1.8 A17 B17, respectively). Patients B10 had more pronounced SIR (C-reactive protein, 111.38±52.5 mg / l) larger volume ground-glass opacity (38.3±9.6 %). At first stage, higher values ventricular global longitudinal strain (RV GLS) detected compared (23.2±4.8 % vs. 19.9±3.5 %, р=0.048). During intensity positive dynamics CT, lower Е А observed B17 (1.0 [0.98; 1.2]) А17 (1.4 [1.18; 1.5, p=0.015), е' a' (0.66 [0.58; 0.85]) 0.95 [0.79; 1.12] (p=0.010). ratios correlated total lactate dehydrogenase fraction (r= -0.452 p=0.006; r= -0.334 p=0.050, respectively).Conclusion In severe intensity, changes parameters that reflected RV diastolic dysfunction observed.