Cytochrome P450 system components and nitric oxide synthase activity in mouse liver under conditions of retinoid stores absence

• DOI: 10.18097/pbmc20125805549
• Publication Date: 2015-04-24T08:33:37Z
• Authors: G.P. Kopylchuk; I.A. Shmarakov; I.M. Buchkovska; M.M. Marchenko; W.S. Blaner
• Keywords: Demethylase

p-Hydroxylase and N-demethylase activities of cytochrome P450 system, NO-synthase activity the intensity nitric oxide superoxide anion production in mitochondrial, postmicrosomal microsomal cellular fractions were studied mouse liver under conditions retinoid stores absence.It is determined, that absence activation occurring with decreased p-hydroxylase system. The results generation analysis showed level NO О2- mitochondrial fraction knock-out mice, changes NADPH-dependent cells.