Fourier transform infrared spectrometer analysis and antimicrobial screening of ethanolic extract of Operculina terpathum from cholistan desert

• DOI: 10.18549/pharmpract.2022.2.2647
• Publication Date: 2022-07-11T09:44:53Z
• Authors: Arslan Ashfaq; Ghazala Shaheen; Anum Khawar; Qurratul Ain Jamil; Rashida Parveen; Faheem Hadi; Aymen Owais Ghauri; Jafir Hussain Shi...; Hafiz Muhammad Asif; Tahira Shamim; Laila Sumreen; Tanveer Ali; Muhammad Akram; Raessa Noor; Amna Mehmood; Farhan Sajid
• Keywords: Bacillus pumilus

Aim of present study was to assess pharmacological (antioxidant, antibacterial & antifungal) potential Operculina terpathum seeds. Ethanolic extract prepared and its phytochemical evaluation show the different chemical compounds such as carbohydrates, phenols, tannin, flavonoids, cardiac glycosides, steroids, alkaloids proteins. FTIR spectra showed presence organic acids, hydroxyl phenolic compounds, amino groups, aliphatic functional groups amide, ketone, aldehyde, aromatics halogen compounds. Antioxidant activity alcoholic performed by DPPH method it 97.13%whereas IC50±SEM (µg/ml) 1.425±0.16. Antibacterial against bacterial strains results were comparable with that standard. Maximum exhibited Bacillus subtillis (28.33±2 mm) pumilus (25.33±2 respectively. Antifungal also maximum Aspergillus flavous Candida albicans6±1, 5±1mm These has good antifungal microbes could be used an alternative antibiotics, antibiotics resistance is very common now a days.