Patterns of Adherence to Oral Atypical Antipsychotics Among Patients Diagnosed with Schizophrenia

• DOI: 10.18553/jmcp.2016.22.11.1349
• Publication Date: 2016-10-26T17:57:24Z
• Authors: Joanna P. MacEwan; Felicia M. Forma; Jason Shafrin; Ainslie Hatch; Darius N. Lakdawalla; Jean-Pierre Linde...
• Keywords: Discontinuation; Medication Adherence; Diagnosis of schizophrenia

Poor medication adherence contributes to negative treatment response, symptom relapse, and hospitalizations in schizophrenia. Many health plans use claims-based measures like possession ratios or proportion of days covered (PDC) measure patient antipsychotics. Classifying patients solely on the basis a single average PDC measure, however, may mask clinically meaningful variations over time how arrive at an level.