Clinicopathologic study of invasive micropapillary carcinoma of the breast

• DOI: 10.18632/oncotarget.16405
• Publication Date: 2017-03-21T09:27:41Z
• Authors: Shen-li Tang; Ji-qiao Yang; Zheng-gui Du; Qiu-wen Tan; Yu-ting Zhou; Di Zhang; Qing Lv
• Keywords: Lymphovascular invasion; Breast carcinoma; Progesterone receptor

// Shen-li Tang 1, 2 , Ji-qiao Yang Zheng-gui Du Qiu-wen Tan Yu-ting Zhou Di Zhang and Qing Lv 1 Department of Breast Surgery, West China Hospital/West School Medicine, Sichuan University, 610041, P.R. Laboratory Disease, Correspondence to: Lv, email: [e-mail] Keywords: breast cancer, invasive micropapillary carcinoma, locoregional recurrence, prognostic factors, survival Received: September 20, 2016     Accepted: February 21, 2017     Published: March 2017 ABSTRACT Invasive carcinoma (IMPC) is a rare subtype carcinoma. It presumed to be more aggressive than ductal (IDC), though it uncertain whether the prognoses IMPC IDC differ. In this retrospective study, we compared clinicopathologic characteristics between 170 female patients with (pure or mixed IDC) 728 pure IDC. The had higher clinical stages histologic grades, incidences lymphovascular invasion axillary lymph node extracapsular extension, degree involvement patients. Moreover, was associated increases in estrogen receptor (ER) progesterone (PR) positivity HER-2 overexpression. Although recurrence-free (LRRFS) (RFS) were poorer patients, overall distant metastasis did not differ two groups. Multivariate analysis revealed that an independent factor for LRRFS RFS We therefore suggest improve treatment decisions, tested presence specific subtype.