Trigger pSA predicting recurrence from positive choline PET/CT with prostate cancer after initial treatment

Choline
DOI: 10.18632/oncotarget.24318 Publication Date: 2018-01-25T11:58:40Z
ABSTRACT
// Junbao Wei 1, * , Hengzong Zhu 2, and Xiaoli Liao 3 1 Department of Therapeutic Radiology, Guangxi Autonomous Regional Cancer Hospital & Medical University, Nanning, 530021, China 2 General Medicine, Longan Traditional Chinese 532700, The Oncology Department, These authors contributed equally to this work Correspondence to: Liao, email: 121021866@qq.com Keywords: prostate cancer; recurrence; choline PET/CT; PSA; meta-analysis Received: July 27, 2017 Accepted: December 13, Epub: January 24, 2018 Published: March 06, ABSTRACT Purpose: To assess the relationship between diagnostic accuracy Choline positron emission tomography/computed tomography (PET/CT) trigger prostate-specific antigen (PSA) level in patients with a biochemical recurrence cancer. Materials Methods: A was conducted synthesize data across multiple studies. Results: pooled sensitivity specificity PET/CT were 82% (95% Confidence Interval (CI):80–84%) 92% (95%CI: 90–93%), respectively. 18 F-choline 81% 78–84%) 90% 85–93%), 11 C-choline 83% CI: 80–86%) 90–94%), detection rate 58% 48–68%) 49–68%), Conclusions: Trigger PSA is an important risk factor for positive findings recurrent cancer increased parallel raises PSA-values. got higher while > 2ng/ml.
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