An Experimental Study on the Establishment of Pulmonary Hypertension Model in Rats induced by Monocrotaline

• DOI: 10.18686/aem.v9i1.161
• Publication Date: 2020-07-03T02:42:01Z
• Authors: Zhongshuang Zhang; Xiaoyong Song; Zhengyong Zhao; Jiazheng Xu; Shu Luo; Jiawang Ma; Ruiyang Zhao; Jiahao Fu; Xudong Wang; Wenxin Zhu; Yaohui Hu; Chunyuan Xue; Yongxiang Liu; Jinniu Guo; Ruihong Lu; Youzhi Wu; Wenxing Gao; Bowen Wu; Wenwei Li; Guohong Gong; Runze Shi; Guangsen Lu
• Keywords: Rat model

Pulmonary hypertension is called PH for short. It caused by the pulmonary artery vascular disease leading to resistance, and increase right lung compartment load, which resulting in weakening or even collapse of ventricular function. The establishment rat model under action monocrotaline a repeatable, simple accessible operation technique, has been widely used treatment hypertension. This paper discusses principle properties on rats action.