High Prevalence of Helicobacter pylori Detected by PCR in the Oral Cavities of Periodontitis Patients

• DOI: 10.1902/jop.2003.74.1.129
• Publication Date: 2005-02-02T12:31:16Z
• Authors: Makoto Umeda; Hiroaki Kobayashi; Yasuo Takeuchi; Joichiro Hayashi; Yoko Morotome‐Hay...; Kazuko Yano; Akira Aoki; Toshifumi Ohkusa; Isao Ishikawa
• Keywords: Dental plaque

Helicobacter pylori has been associated with the development of peptic ulcers and gastric cancer. Although it may be transmitted through oral cavity, is unknown whether cavity acts as a permanent reservoir for this bacterium. The purpose study was to use nested polymerase chain reaction (PCR) clarify H. pylori.The existence in determined by PCR 57 subjects culture method 18 subjects. presence periodontopathic bacteria also 16S rRNA-based method.Although rarely detected technique, frequently (35.1%) especially among periodontitis patients who had bacterium gastrointestinal tract (46.4%). Among harbored stomach or duodenum, 41.2% periodontal pockets > = 4 mm 9.1% without showed dental plaque, although statistically significant difference not observed. One patient retained even after eradication from duodenum. Most (8/10) plaque Bacteroides forsythus their cavities.Close attention should given harbor cavity.