[Famous veteran traditional Chinese medicine doctors' medication rules in treating spermatorrhea].

• DOI: 10.19540/j.cnki.cjcmm.20181128.002
• Publication Date: 2019-03-01
• Authors: Xiangjun Qi; Tengyu Chen; Zhaoping Zhang; Caishan Fang; Guoming Chen; Xueyan Chen; Yi-Qian Lu; Yue-Mei Chen; Haorui Liang; Jian-ying Lang
• Keywords: China; Drug Combinations; Physicians; Medicine, Chinese Traditional; 01 natural sciences; 0104 chemical sciences; Drugs, Chinese Herbal; Veterans

To explore famous veteran traditional Chinese medicine( TCM) doctors' medication rules in treating spermatorrhea based on the medical cases about collected from Hundred TCM Clinical Doctors of Years China and Proven Cases National Medical Master Test Case. Researchers extracted such data as medicinal therapies these according to inclusion exclusion criteria. Then,Excle 2010,SPSS Clementine 12. 0 SPSS 22. were adopted respectively for frequency analysis,association analysis,cluster analysis factor analysis. Cluster was carried out by Ochiai algorithm binary variable data,one systematic clustering methods. And principal component used Finally,27 41 prescriptions included total. The showed that most common therapy astringent therapy( n = 28),which followed tonifying method,tranquilizing method,heat-clearing method,damp-dispelling method Qiregulating method. top three kinds high-frequency medicines Poria,Ostreae Concha Dioscoreae Rhizoma. association found 11 medicine pairs,23 combinations herbs 6 five herbs. Among them,the representatives Rubi Fructus→Fossilia Ossis Mastodi,Rehmanniae Radix Praeparata + Corni Fructus→Dioscoreae Rhizoma,and Pinelliae Rhizoma→Citri Reticulatae Pericarpium,which therapeutic characteristics astringing,tonifying kidney replenishing essence,fortifying spleen dispelling dampness. Moreover,7 groups with relevance tree map generated cluster analysis,including " Phellodendri Chinensis Cortex Anemarrhenae Rhizoma" Angelicae Sinensis Radix,Rehmanniae Radix,Bupleuri Glycyrrhizae et Rhizoma",which demonstrated effects nourishing Yin purging fire,tonifying soothing liver. Besides,totally 12 factors obtained 14 drug combinations,like Amomi Fructus,Anemarrhenae Rhizoma Cortex" Nelumbinis Stamen,Moutan Cortex,Poria Scrophulariae Radix",which indicated compatibility fire,dispelling dampness clearing heat. In conclusion,data mining techniques( including analysis) comprehensively analyze spermatorrhea,which helpful guiding clinical practice TCM.