[A Preliminary Study on Genetic Polymorphism of 12 Rare Blood Group of Dongxiang Nationality in Gansu Province].

• DOI: 10.19746/j.cnki.issn.1009-2137.2025.02.036
• Publication Date: 2025-04-01
• Authors: Jia-Dong Ding; Yiyuan Wang; Xiaoping Zhang
• Keywords: Han nationality

To detect the alleles of 12 blood group systems (Rh, MNS, Duffy, Kidd, Kell, Diego, Dombrock, Yt, Colton, Scianna, Lutheran and Lw) Dongxiang ethnic in Gansu province, understand characteristics rare common group, order to provide a basis for safe transfusion establishment gene bank. The were classified by polymerase chain reaction (PCR) 100 people from differences frequency compared other areas China analyzed. allele frequencies Rh, Dombrock province similar northern regions. Duffy system exhibited specificity, with lower than most southern regions as well There no significant Kell Diego China. Lua was higher all China, which might be associated genetic variation or sample selection size. Scianna Lw genes showed monomorphic distribution, genotypes YtaYta, CoaCoa, Sc1Sc1 LwaLwa, respectively. show polymorphic while distribution. distribution among has its own specificity.