Optimization of the Extraction Process for Bioactive Compounds from the Root Barks of Moringa oleifera

• DOI: 10.20307/nps.2023.29.4.281
• Publication Date: 2024-01-19T04:35:37Z
• Authors: Do Hoang Giang; Tran Van Hien; Nguyen Thi Thu Minh; Nguyen Thu Uyen; Hoang Thuy Duong; Bui Thi Nhat Le; Mai Thi Thu Ha; Nguyen Tien Dat
• Keywords: Moringa; Scavenging

The optimal condition for Moringa oleifera root barks extraction was determined using response surface methodology and Box-Behnken Design. actual of the factors 65℃, ethanol 60%, 40 (mL/g) liquid-to-solid ratio with 240 minutes time. enrichment phenolic compounds sharply affected antioxidant, inhibitions α-amylase enzyme, as well as, anti-inflammatory effect extract from M. barks. in exhibited better 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging inhibitory activities than those positive controls. Also, showed weak hydroxyl nitric oxide (NO) production effects. These revealed a simple promising method preparation bioactive products bark oleifera.