Thymoma Profile at Dr. Moewardi General Hospital: Does Thymoma Size Really Affect Distant Metastasis?

• DOI: 10.20473/jr.v10-i.1.2024.30-35
• Publication Date: 2024-02-28T07:07:56Z
• Authors: Novita Silvana Th...; Fahlevie Fahlevie; Ana Rima Setijadi; Widiastuti Widias...; Sastia Rakhma
• Keywords: profile; R; cancer; metastasis; Medicine; thymoma; mediastinal mass

Introduction: Size is a predictor factor of patient’s prognosis and metastasis in solid tumors. This study determined the relationship between thymoma size distant metastasis. Methods: A cohort retrospective using medical record data was conducted at Dr. Moewardi General Hospital, Surakarta, from January 2019 to August 2021. Of 1,430 thoracic oncology patients, 150 (10%) had mediastinal mass with as majority (48.6%). About 73 patients were included. The dependent variable, (distant non-distant) independent variable. cut-off point receiver operating characteristic (ROC) analysis. correlation analyzed Chi-Square test, p < 0.05 considered significant. Results: Thymoma predominated by males (53.4%), mean age 43 ± 16 years old, dyspnea most common symptom. Metastatic lesions found 87.7% metastatic sites intrathoracic (79.5%), followed axillary lymph nodes (49.3%), bone (21.9%), liver (20.5%), brain (1.4%). value 8.25 cm, indicating that >8.25 cm categorized large thymoma. Distant 86.0% patients. tumors tend spread into various (OR = 5.39; 95% CI 2.8-32.6; 0.002). Conclusion: must be taken account when there are male their forties presented mass. for can predict