Serological Testing for COVID-19 in the Fertility Setting: The Lockdown Impact and Subsequent Dynamics Reflected in the Seroprevalence of Sars-Cov-2 Antibodies

• DOI: 10.20944/preprints202101.0024.v1
• Publication Date: 2021-01-04T11:32:59Z
• Authors: Corina Manolea; andrei capitanescu; anca pop; roxana bors; ioana rugescu; melihan bechir; claudia mehedintu; valentin varlas
• Keywords: Seroprevalence; Seroconversion; Triage

The COVID-19 pandemic had profound negative effects on millions of couples affected by infertility and in need to resort assisted reproductive technologies. There is no consensus over the optimal way moment screening triage-negative asymptomatic patients staff. We present SARS-CoV-2 antibodies’ (IgM, IgG) seroprevalence 516 30 fertility care providers. sampling for serological assays took place from lockdown release throughout second half 2020 (17.05 - 01.12.2020). It revealed an increased antibodies that closely followed local epidemiology COVID-19, with highest rate seropositivity coincident peak wave. From 546 individuals whose blood samples were assessed antibodies, 6% yielded positive results. overall seroconversion was 2.8% IgG 5.1% IgM. In group IgM, we observed a predictive value IgM 98.36% (95% CI: 88.79 – 99.78%), which clinically meaningful. Serological testing up seven days prior actual procedure might avoid more expensive not sensitive molecular currently being used patient most units.