First Detection and Co-occurrence of kdr (F1534C and S989P) Mutations in Multiple Insecticides Resistant Aedes aegypti in Nigeria

• DOI: 10.20944/preprints202107.0302.v1
• Publication Date: 2021-07-14T07:21:22Z
• Authors: Ifeoluwa Kayode F...; Emmanuel Taiwo Idowu; Tolulope Amos Oye...; Adedapo O. Adeogun; Kemi Adesalu; Oge Nwanya; Felix Okonkwo; Yusuf Oladosu; Olubunmi Otubanjo
• Keywords: 0303 health sciences; 03 medical and health sciences; anatomy_morphology; 3. Good health

The outbreak of yellow fever transmitted by Aedes aegypti has been major concern in Nigeria, this mosquito also transmits several other arboviruses globally. control many the borne diseases relies heavily on use insecticides. Therefore, constant monitoring insecticide resistance status and associated mechanisms crucial within local population. Here, we determined profile adult from Ikorodu Local Government Area Lagos State, Nigeria to different classes insecticides using WHO procedures. presence kdr mutations F1534C, S989P V1016G were among resistant populations molecular methods. High level DDT pyrethroid was rec-orded study, though possible deltamethrin reported one locations. Resistance bendiocarb recorded Majidun community while both locations susceptible malathion. F1534C mutation with detected for first time singly co-occurrence Africa. role these phenotype expressed study area need established.