The Influence of the Dispersing Agent Nature on the Interaction of DNA Nucleotides with the Surface of YSZ Nanoparticles and the Homogeneity of Lyophilites Based on Them

• DOI: 10.20944/preprints202210.0152.v1
• Publication Date: 2022-10-11T13:11:06Z
• Authors: Aleksander S. Dor...; Viktor S. Doroshk...; Tatyana Yu. Zelenyak; Nelya V. Doroshke...; Andriy I. Lyubchyk; Sergiy I. Lyubchyk; Svitlana B. Lyubchyk; Alisa A. Tatarinova; Anca Stanculescu; Dan Chicea; Carmen Mita; Nicoleta Cornei; Diana Mardare; Boris L. Oksengen...; Nadejda N. Nikifo...; Matlab N. Mirzayev; Evgeni P. Popov; Aleksandr A. Donkov; Vesna Teofilović; Bozena Jasinska; Le Hong Khiem

A variational analysis of dispersion medium (electrolytes and surfactants) was carried out for the best nucleotide interactions with the presence of nanoparticles and the ability to formation of homogeneous coatings upon drying / lyophilization. Using UV-spectroscopy and transmission electron microscopy, the processes of immobilization of nucleotides on the surface of nanoparti-cles of the composition ZrO2-3mol% Y2O3 (YSZ) in the presence of various dispersing agents were investigated. Promising dispersing agents were established, the optimal composition of suspen-sions based on DNA nucleotides and YSZ nanoparticles, which is potentially suitable for adaptive technologies of bionanoelectronics, was selected. The aim of the work is to obtain and study functional media for molecular electronics based on heterojunctions biological molecule – wide-gap dielectric.