Efficacy of Polyhexamethylene Biguanide (Polyhexanide or PHMB) in Pediatric Superficial Partial-Thickness Burns: Outcomes and Influencing Factors

• DOI: 10.20944/preprints202403.1513.v1
• Publication Date: 2024-03-29T03:32:45Z
• Authors: Aba Lőrincz; Hermann Nudelman; Anna Gabriella La...; András Garami; Krisztina Adrienn...; Tamás Zoltán Kovács; Gergő Józsa
• Keywords: Biguanide

In pediatric burn care, achieving swift healing with minimal complications remains paramount. This investigation assesses polyhexamethylene biguanide (PHMB)'s role in managing superficial partial-thickness burns children, focusing on the effects of various patient-specific factors recovery. Through a retrospective analysis 27 cases treated PHMB, we explored impact age, size, dressing frequency, treatment delay, cold therapy application, and analgesic usage duration until reepithelialization. Notably, majority patients benefited from early therapy, yet only 1 3 received analgesics. The study reveals mean time 8.78 days, extent showing strong correlation to recovery speed. Most treatments were managed outpatient, evidenced by negligible average hospital stay. Impressively, intervention recorded no complications. Our findings endorse PHMB as promising for second-degree young patients, offering efficiency par or surpassing traditional methods, without increasing complication risks. underscores necessity continued exploration into optimal application prehospital interventions comprehensive benefits management, advocating future research aimed at assessing long-term outcomes, including scar quality patient satisfaction.