Respiratory Symptoms and Changes of Oxidative Stress Markers among Motorbike Drivers Chronically Exposed to Air Fine and Ultrafine Particle: The Case of Douala and Dschang, Cameroon

• DOI: 10.20944/preprints202405.0862.v1
• Publication Date: 2024-05-14T03:46:45Z
• Authors: Joseph Eloge TIEKWE; Nadine Ongbayokolak; Solange Dabou; Natheu Kamhoua Cerge; Marie Stéphanie Goka; Prosper Cabral Bi...; Isabella Annesi-M...; Phélix Bruno Telefo
• Keywords: Particle (ecology)

Recent studies releaved that the high production of reactive oxidative species due to exposure fine or ultrafine particles are implicated in many chronical respiratory disorders. However, poor standard clinical data sub-Saharan countries makes very difficult assessment knowledge air pollution health impact urban cities. Objective: aim this study was evaluate distribution disorders associated and through changes some stress biomarkers among motorbike drivers from two cities Cameroon Methods: A cross-sectional survey using a standardized questionnaire conducted 2019 on 191 motorcycle (MD) working Douala Dschang. Then, activity superoxide dismutase (SOD) level malondialdehyde (MDA) were measured by colorimetric methods. The participants after clustered Excel Microsoft analysed statistically compared Spss 2.0 software. Results: recruited both aged 21 40, with mean age 29.93 (± 0.82). as running nose, cold, dry cough, chest discomfort, breathlessness, significantly increased MD Douala. According results biological assays, SOD MDA, more Douala, those change these markers correlated mobilization neutrophils Monocytes showing initiation evolution subjacent inflammatory reactions, seemed be influenced place habitation MD. Conclusion: Through it is confirmed evidence long-term active people Urban Further should analysis provide cellular damage dysfunction related chronically PM metropolitan Africa context.