Vaccine Unawareness: Analysis of the Mediating Effect Between Health Literacy and Vaccination Attitudes

• DOI: 10.20944/preprints202505.1297.v1
• Publication Date: 2025-05-19T02:18:33Z
• Authors: Valentina Saviozzi; Mirko Duradoni; Marina Baroni; Giulia Colombini; Marco Del Riccio; Noemi Gori; Nicolò Della Magg...; Ester Macrì; Letizia Materassi; Andrea Guazzini; Patrizio Zanobini
• Keywords: Health Literacy

Background: This study aims to explore the relationship between Health literacy (HL), vaccination behaviors and Vaccination unawareness (VU) by trying understand how HL influences attitudes potential mediation of VU. Methods: Data were collected using HLS-EU-Q16, Attitude Scale Vaccine Unawareness Scale. Results: The results show that 17.3% variance in total VAX-I is explained predictors. Among significant predictors, low VU age positively predicts VAX-I, while adequate negatively VAX-I. Analyses for specific dimensions reveal predict distrust benefits, concerns about future effects, profit, preference natural immunity, these dimensions. Mediation analysis showed significantly mediates contributing 44% effect percentages 35% 54% Conclusions: Results lower levels VU, combined with higher HL, are associated more positive toward vaccines. suggest increasing alone may be necessary but not sufficient improve attitudes; therefore, interventions should focus only on also decreasing