PADI1 contributes to EMT in PAAD by activating the ERK1/2-p38 signaling pathway

• DOI: 10.21037/jgo-21-283
• Publication Date: 2021-06-23T09:59:24Z
• Authors: Tengfei Ji; Keqiang Ma; Liang Chen; Tiansheng Cao
• Keywords: 0301 basic medicine; 0303 health sciences; 03 medical and health sciences; 3. Good health

Background: Peptidylarginine deiminase 1 (PADI1) has been reported to promote tumorigenesis in breast cancer. However, the functional role of PADI1 pancreatic ductal adenocarcinoma (PAAD) remained elusive until now.