Pure red cell aplasia associated with thymoma: a report of a single-center experience

• DOI: 10.21037/jtd.2018.07.14
• Publication Date: 2018-08-30T07:45:16Z
• Authors: Satoru Moriyama; Motoki Yano; Hiroshi Haneda; Katsuhiro Okuda; Osamu Kawano; Tadashi Sakane; Risa Oda; Takuya Watanabe; Ryoichi Nakanishi
• Keywords: Thymectomy; Single Center

Pure red cell aplasia (PRCA) associated with thymoma is relatively rare, and relevant reports are limited. We investigated the clinical features outcomes of PRCA in this study.A retrospective review all patients who underwent surgical resection from April 1, 2004, to December 31, 2015, was performed.We experienced eight among 146 thymoma. Extended thymectomy (n=4) were performed for Regarding WHO classification thymoma, subtypes type B2 or B3 seven patients, stage advanced patients. Complete achieved macroscopically only five Recurrence occurred four complete resection. diagnosed after six (range 1-101 months, median 56.5 months). Cyclosporine used Pneumonia treatment-related complications due cyclosporine The follow-up period ranged 13-147 months (median 54.5 months) diagnosis. Three obtained remission anemia by cyclosporine. Although one patient able stop taking because anemia, transfusion needed relapse PRCA. Five died, main causes death as pneumonia cardiac failure (n=1).PRCA postoperatively three-quarter should be alert occurrence even especially incomplete disease. effective PRCA, but occurred, particularly pneumonia. As treatment its combined a complex manner, treating can quite difficult.