Triglyceride to high-density lipoprotein cholesterol ratio as a risk factor of repeat revascularization among patients with acute coronary syndrome after first-time percutaneous coronary intervention

• DOI: 10.21037/jtd.2019.12.26
• Publication Date: 2020-01-01T05:06:02Z
• Authors: Ya-Min Su; Rui Zhang; Rong-Feng Xu; Hong-Lei Wang; Hai-Hua Geng; Min Pan; Yang-Yang Qu; Wen-Jie Zuo; Zhen-Jun Ji; Gen-Shan Ma
• Keywords: 03 medical and health sciences; 0302 clinical medicine; 3. Good health

Background: It is clinically important to identify high-risk patients with acute coronary syndrome (ACS) who may require repeat revascularization. This retrospective study identified risk factors for revascularization among ACS after first-time successful percutaneous interventions (PCIs). The predictive value of the triglyceride high-density lipoprotein cholesterol (TG/HDL-C) ratio was also evaluated. Methods: We enrolled consecutive had angiography performed during period from 6 12 months a PCI. primary outcome subjects were stratified based on PCI events. After comparing various clinical characteristics, univariate and multivariate Cox proportional hazard model analyses adopted evaluate effects Results: (n=271) divided into event (+) group (n=101) (−) (n=170). In group, target lesion (TLR) accounted 20.79% vessel (TVR) 50.49% patients. contrast, 52.47% required de novo (DVR). adjustment confounding factors, TG/HDL-C [hazard (HR) =1.206, 95% confidence interval (CI): 1.016–1.431, P=0.032 each higher unit] Gensini score (HR =1.012, CI: 1.005–1.018, P<0.001 unit) independent Subgroup showed that ratios associated significantly PCIs in male, hypertensive, diabetes mellitus subgroups. Conclusions: could serve as