Risk Factors for Failure After 1-Stage Exchange Total Knee Arthroplasty in the Management of Periprosthetic Joint Infection

• DOI: 10.2106/jbjs.18.00947
• Publication Date: 2019-06-20T08:53:58Z
• Authors: Mustafa Citak; Jasmin Friedenstab; Hussein Abdelaziz; Eduardo M. Suero; Akos Zahar; Jochen Salber; Thorsten Gehrke
• Keywords: Adult; Aged, 80 and over; Male; Arthritis, Infectious; Prosthesis-Related Infections; Middle Aged; Prosthesis Failure; 3. Good health; 03 medical and health sciences; Logistic Models; 0302 clinical medicine; Risk Factors; Odds Ratio; Humans; Female; Arthroplasty, Replacement, Knee; Knee Prosthesis; Aged; Retrospective Studies

Background: One-stage exchange arthroplasty in the management of periprosthetic joint infection was introduced at our institution. The purpose this study to analyze risk factors failure after following total knee treated with 1-stage exchange. Methods: Ninety-one patients who underwent failed treatment due from January 2008 December 2017 were included. From same period, we randomly selected a 1:1 matched control group without subsequent revision surgical procedure. Bivariate analyses, including preoperative, intraoperative, and postoperative factors, as well logistic regression, performed identify for failure. Results: analysis yielded 10 predictors (variables significance p < 0.05) involving re-revision any reason 11 reinfection. binary regression model revealed reason: history (odds ratio [OR], 26.706 [95% confidence interval (CI), 5.770 123.606]; 0.001), 2-stage (OR, 3.948 CI, 1.869 8.339]; isolation enterococci 16.925 2.033 140.872]; = 0.009). reinfection or arthroplasty, enterococci, streptococci 6.025 1.470 24.701]; 0.013). Conclusions: We identified several infection, most which not related patient comorbidities. Among them, previous Enterococcus Streptococcus species associated higher Besides multidisciplinary approach, being aware when evaluating could lead better outcomes. Level Evidence: Prognostic III . See Instructions Authors complete description levels evidence.