Low Preoperative Albumin Levels Predict Adverse Outcomes After Total Joint Arthroplasty

• DOI: 10.2106/jbjs.19.00511
• Publication Date: 2020-02-21T05:12:37Z
• Authors: Deena Kishawi; Garrett Schwarzman; Alfonso Mejia; Awais K. Hussain; Mark H. Gonzalez
• Keywords: Hypoalbuminemia; Univariate analysis; Quartile

Background: Low albumin levels have previously been shown to be a risk factor for increased complications in the 30-day postoperative period after total hip or knee arthroplasty. In this study, we examined effect that on all joint primary arthroplasties revisions (shoulder, elbow, wrist, hip, knee, ankle, and fingers). Methods: Patients who underwent arthroplasty revision from 2005 2015 had preoperative serum concentration recorded were identified U.S. National Surgical Quality Improvement Program (NSQIP) database. grouped into those with normal concentrations (≥3.5 g/dL) hypoalbuminemic (<3.5 g/dL); hypoalbuminemia was subdivided quartiles statistical analysis. Univariate analyses conducted use of Student t test categorical outcomes chi-square continuous variables. Following univariate analysis, significant comorbidity variables both groups used multivariate regression analysis determine independent association outcomes. Results: Using available data 2015, 135,008 patients fit eligibility criteria, including undergone (n = 125,162) 9,846). The included shoulder (2%), (46%), (52%), (3%), (39%), (57%), other (1%). We found lower greater rate cardiac arrest, myocardial infarction, cerebrovascular accident, organ space surgical site infection, sepsis, septic shock, pneumonia, renal insufficiency general, unplanned intubation, return operating room within 30 days, urinary tract wound infection (all p < 0.005). Conclusions: There difference between low revisions. at significantly adverse Further research is needed develop interventions improve preoperatively mitigate Level Evidence: Prognostic IV . See Instructions Authors complete description evidence.