Risk Factors for Surgical Site Infection Following Orthopaedic Spinal Operations

• DOI: 10.2106/jbjs.f.01515
• Publication Date: 2008-01-02T16:58:33Z
• Authors: Margaret A Olsen; Jeffrey J Nepple; K Daniel Riew; Lawrence G Lenke; Keith H Bridwell; Jennie Mayfield; Victoria J Fraser
• Keywords: Univariate analysis; Surgical Site Infection

Surgical site infections are not uncommon following spinal operations, and they can be associated with serious morbidity, mortality, increased resource utilization. The accurate identification of risk factors is essential to develop strategies prevent these potentially devastating infections. We conducted a case-control study determine independent for surgical infection orthopaedic operations.We performed retrospective patients who had an operation at university-affiliated tertiary-care hospital from 1998 2002. Forty-six superficial, deep, or organ-space were identified compared 227 uninfected control patients. Risk determined univariate analyses multivariate logistic regression.The overall rate during the five years was 2.0% (forty-six 2316). Univariate showed serum glucose levels, preoperatively within days after operation, significantly higher in whom developed than Independent that by analysis diabetes (odds ratio = 3.5, 95% confidence interval 1.2, 10.0), suboptimal timing prophylactic antibiotic therapy 3.4, 1.5, 7.9), preoperative level >125 mg/dL (>6.9 mmol/L) postoperative >200 (>11.1 3.3, 1.4, 7.5), obesity 2.2, 1.1, 4.7), two more residents participating operative procedure 1.0, 4.7). A decreased operations involving cervical spine 0.3, 0.1, 0.6).Diabetes highest infection, elevated also independently infection. role hyperglycemia as factor previously diagnosed should investigated further. Administration antibiotics one hour before increasing dosage adjust important decrease operations.